yemenjmedYemen Journal of MedicinecoVolume 4 Issue 3MultidisciplinaryEnglishSeptember- December 2025NNY20251231ArticleHematological Parameters and Iron Status in Pregnant Women in Conflict-Affected Taiz, YemenEnglishY624629Radfan SalehAbdullah1EnglishNMansour Abdulnabi H.Mehdi2EnglishYNaif TalebAli1EnglishY10.63475/yjm.v4i3.0193Background: Iron deficiency anemia persists as a serious public health concern in conflict-affected settings, with Yemen exhibiting among the highest global prevalence rates. This cross-sectional study evaluates trimester-specific hematological changes and iron levels among pregnant women in Taiz, Yemen—a region devastated by persistent humanitarian crises. Methods: A cross-sectional study was conducted from January to March 2022. A total of 165 pregnant women (15–40 years) were systematically enrolled from antenatal clinics. Complete blood count and serum iron were analyzed. Statistical analyses included analysis of variance (ANOVA) and multivariable regression. Results: Stratification by trimester revealed significant progressive declines in hemoglobin, serum iron, and red blood cell indices from the first to the third trimester (all p < 0.01). Overall, 41.8% of participants exhibited anemia (hemoglobin < 11.0 g/dL), with the prevalence escalating to 57.8% in the third trimester. Iron deficiency (serum iron < 60 μg/dL) was found in 28.5% of the women. Multivariable analysis identified illiteracy (adjusted β = −1.2 [95% CI, −2.2 to −0.2]; p = 0.02) and grand multiparity (adjusted β = −1.1 [95% CI, −1.9 to −0.3]; p = 0.007) as independent predictors of lower hemoglobin levels. Conclusions: Trimester-dependent declines in hemoglobin and red blood cell parameters are common during pregnancy. However, in conflict-affected regions, these changes are often more severe, likely due to iron deficiency and limited access to proper screening and care.EnglishHematological parameters, serum iron, pregnancy, anemia, Yemen, Taizhttps://yemenjmed.com/admin/abstract?id=302References1619