yemenjmedYemen Journal of MedicinecoVolume 2 Issue 2 MultidisciplinaryEnglishMay-August 2023NNY20230928ArticleA rare case of childhood interstitial lung disease attributed to desquamative interstitial pneumoniaEnglishY112114SamikshaKamble1EnglishNKetakiUtpat2EnglishYGayathriAmonkar3EnglishYUnnatiDesai2EnglishY10.32677/yjm.v2i2.4098Desquamative interstitial pneumonia is a rare form of interstitial lung disease in children that can be idiopathic but is usually associated with an inborn error of surfactant metabolism. We reported DIP in a thirteen-year-old girl who was referred to our outpatient clinic because of worsening dyspnoea. High-resolution computed tomography showed ground-glass attenuation with honeycombing and intralobular, interstitial septal thickening suggestive of an interstitial lung disease. Transbronchial lung biopsy was performed and histopathology findings were consistent with desquamative interstitial pneumonia. The patient was started on steroid therapy with oxygen support. Unfortunately, she died a month after being diagnosed due to disease progression.EnglishChild interstitial lung disease, Desquamative interstitial pneumonia, Transbronchial lung biopsyhttps://yemenjmed.com/admin/abstract?id=67References1619Clement A, Nathan N, Epaud R, et al. Interstitial lung diseases in children. Orphanet J Rare Dis 2010; 20(5): 1-24.Dinwiddie R, Sharief N, Crawford O. Idiopathic interstitial pneumonitis in children: a national survey in the United Kingdom and Ireland. Pediatr Pulmonol 2002; 34(1):23-9.Fan LL, Kozinetz CA. Factors influencing survival in children with chronic interstitial lung disease. Am J Respir Crit Care Med 1997;156:939-42.Kitazawa H, Kure S. Interstitial lung disease in Childhood: Clinical and genetic aspects. Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine 2015:9(s1) 57-68.Hime NJ, Zurynski Y, Fitzgerald D, et al. Childhood interstitial lung disease a systematic review. Pediatr Pulmonol 2015; 50(12):1383-92.Kurland G, Deterding RR, Hagood JS, et al. American Thoracic Society Committee on Childhood Interstitial Lung Disease (chILD) and the chILD Research Network. An official American Thoracic Society clinical practice guideline: classification, evaluation, and management of childhood interstitial lung disease in infancy. Am J Respir Crit Care Med 2013;188(3):376-94.Popler J, Lesnick B, Dishop MK, et al. New coding in the International Classification of Diseases, Ninth Revision, for childrenand;rsquo;s interstitial lung disease. Chest 2012;142(3):774-80.Cazzato S, di Palmo E, Ragazzo V, et al. Interstitial lung disease in children. Early Hum Dev. 2013;89 (suppl 3):S39-43.Bressieux-Degueldre S, Rotman S, Hafen G, et al. Idiopathic Desquamative interstitial pneumonia in a child: a case report. BMC Research Notes 2014; 7:383.Dishop MK. Diagnostic pathology of diffuse lung disease in children. Pediatr Allergy Immunol Pulmonol 2010; 23(1):69-85.Clement A, Force ERST. Task force on chronic interstitial lung disease in immunocompetent children. Eur Respir J 2004; 24(4):686-697.Vece TJ, Fan LL. Interstitial lung disease in children older than 2 years. Pediatr Allergy Immunol Pulmonol 2010; 23(1):33and;ndash;41.Bokulic RE, Hilman BC. Interstitial lung disease in children. Pediatr Clinand;nbsp; North Am 1994; 41(3):543and;ndash;567.Sheth KJ, Leichter HE, Kishaba G, et al. Focal segmental glomerulosclerosis in desquamative interstitial pneumonia.and;nbsp;Child Nephrol Urol.and;nbsp;1992;12(1):43and;ndash;46Tazelaar HD, Wright JL,Churg A. Desquamative interstitial pneumonia. Histopathology 2011; 58 (4):509-516.Diken and;Ouml;E, Şengand;uuml;l A, Beyan AC, et al. Desquamative interstitial pneumonia: Risk factors, laboratory and bronchoalveolar lavage findings, radiological and histopathological examination, clinical features, treatment and prognosis. Exp Ther Med 2019;17(1):587-595.