yemenjmedYemen Journal of MedicinecoVolume 2 Issue 3MultidisciplinaryEnglishSeptember-DecemberNNY20231219ArticleDoes khat chewing hurt the heart? A debate or fact?EnglishY186186AymanEl-MenyarEnglishN10.32677/yjm.v2i3.4295I have read with an interest the article written by Aleemallah. The author concluded that based on the available publications, there is no solid evidence that khat chewing has a worse effect on coronary artery disease (CAD) or the heart directly. We disagree with this conclusion as there are plenty of studies on the harmful impact of khat chewing on the cardiovascular system (CVS). Here, I try to summarise some of the supporting literature.Englishhttps://yemenjmed.com/admin/abstract?id=89References1619Aleemallah G. Khat (Catha edulis) as a risk factor for cardiovascular disorders: Controversies and facts. Yemen J Med. 2022;1(2):59-61.Al-Motarreb A, Shabana A, El-Menyar A. Epicardial coronary arteries in khat chewers presenting with myocardial infarction.and;nbsp;Int J Vasc Med.and;nbsp;2013;2013:857019.Ali WM, Al Habib KF, Al-Motarreb A, et al. Acute coronary syndrome and khat herbal amphetamine use: An observational report.and;nbsp;Circulation.and;nbsp;2011;124:2681and;ndash;9Al-Motarreb A, Al-Suwaidi J. Khat Chewing and Cardiovascular Disease. Heart Views. 2022 Apr-Jun;23(2):103-107El-Menyar A, Mekkodathil A, Al-Thani H, et al. Khat use: history and heart failure. Oman Med J. 2015;30(2):77-82.Kassaw EA, Aboye GT, Yilma D.and;nbsp;et al.and;nbsp;The impact of khat chewing on heart activity and rehabilitation therapy from khat addiction in healthy khat chewers.and;nbsp;Sci Rep. 2022;12: 22083.Jayed, D. and Al-Huthi, M. Khat Chewing Induces Cardiac Arrhythmia.and;nbsp;Open Access Library Journal. 2016;3:1-8Mega TA, Dabe NE. Khat (Catha Edulis) as a Risk Factor for Cardiovascular Disorders: Systematic Review and Meta-Analysis. Open Cardiovasc Med J. 2017 Dec 19;11:146-155Al-Motarreb A, Briancon S, Al-Jaber N, et al. Khat chewing is a risk factor for acute myocardial infarction: a case-control study. Br J Clin Pharmacol. 2005;59(5):574-81Radaelli D, Manfredi A, Zanon M, et al. Synthetic Cannabinoids and Cathinones Cardiotoxicity: Facts and Perspectives. Curr Neuropharmacol. 2021;19(11):2038-2048