Gastric Plexiform Fibromyxoma: A Narrative Review of a Rare Mesenchymal Tumor

Sajad Ahmad Salati¹, Ajaz Ahmad Rather²

Keywords: Benign gastric tumor, gastric plexiform fibromyxoma, gastrointestinal stromal tumor, plexiform angiomyxoid myofibroblastic tumor, immunohistochemistry

DOI: 10.63475/yjm.v4i3.0216

DOI URL: https://doi.org/10.63475/yjm.v4i3.0216

Publish Date: 31-12-2025

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Pages: 507 - 513

Views: 4

Downloads: 5

Citation: 0

Author Affiliation:

1 Professor, Department of Surgery, College of Medicine, Qassim University, Buraydah, Saudi Arabia
2 Professor, Department of Surgery, SKIMS Medical College, Srinagar, Jammu and Kashmir, India

Abstract

Gastric plexiform fibromyxoma (GPF) is a rare mesenchymal tumor that primarily affects the stomach, and to date, only about 170 cases have been reported. It is benign in nature with a favorable long-term prognosis. GPF mimics many disease entities, including the malignant ones, and the proper diagnosis differentiation requires a battery of investigations, including imaging, histopathology, immunochemistry, and molecular genetics studies. Management is generally surgical. This article is drafted to revisit various aspects of GPF to enhance the level of awareness in healthcare providers.

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